수상기념 특강

[S2] 학술대상 수상기념 특강


Hei Chan LeeCV
Department of Pharmaceutical Biotechnology,
Sun Moon University, Korea
Synthetic Biology and Global Biosafety

Synthetic biology has evolved since the advent of recombinant DNA technology in 1970s and now become a hero with Nobel Prize in 2020 for pioneering CRISPR-Cas9. Great applications of biotechnology techniques to every aspects of human life including bioelectronics are necessary and essential parts for current world. The problems, however, with biotechnology techniques exist symbiotically from the birth, just like all the great inventions in human history. Research on the "gain-of-function" for highly pathogenic avian influenza virus (HPAI) 1-3 raised lot of questions on the benefits of public information of highly sensitive subjects. Studies on biological agents including all highly pathogenic and serious effects on human, animals and environments are somewhat controlled by regimes formulated nationally and internationally. For better watch and preparedness on the outbreaks such as SARS, MERS, Ebola, and so on, understanding4 on the biological agents must be preceded and the preparedness for the next unknown events can be more appropriate.

References
1. Masaki Imai, et al, Experimental adaptation of an influenza H5 HA confers respiratory droplet transmission to a reassortant H5 HA/H1N1 virus in ferrets (2012), Nature, 486, 420-428
2. Ron A. M. Fouchier, et al, Gain-of-function experiments on H7N9 (2013), Nature, 500, 150-151.
3. Frank Alexander Hamill, National Biosafety standards differ (2017), Nature, 543, 623.
4. Yeong-seon Yoon and Hei Chan Lee, Risk Groups of Biological Agents and Biosafety Level Applications (2019), KSBB Journal, 34(4), 352-358

Keywords
Synthetic Biology, biosafety, DURC, enabling technology, biological weapon
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